IgA nephropathy recurs early in the graft when assessed by protocol biopsy
نویسندگان
چکیده
منابع مشابه
TGF-beta1 expression and chronic allograft nephropathy in protocol kidney graft biopsy.
Chronic allograft nephropathy (CAN) represents a frequent and irreversible cause of long-term renal graft loss. TGF-beta1 is a key profibrogenic cytokine associated with CAN pathogenesis. Because of clinical diagnostic inaccuracy, protocol biopsy has been suggested to be a beneficial method for early CAN detection. Protocol core biopsy was carried out in 67 consecutive cyclosporine-based immuno...
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Now THAT THE RESULTS of kidney transplantation are improving to relatively high rates, we need more sensitive measures of transplant outcome than graft and patient survival. A subjective assessment by the transplant surgeon, evaluated as grade A, B, C. D, or Fat 3 months, 6 months, I year, and annually thereafter has long been available to the UCLA Transplant Registry but has been largely unuse...
متن کاملIgA nephropathy.
A great interest in IgA nephropathy was demonstrated in the last few years. Unfortunately, a complete picture of this chronic disease should not yet been made. The article deals with 7 patients with IgA nephropathy treated in our Institute. The following characteristics were examined during a long period of time (1-17 years): clinical picture, course of the disease, clinical and morphologic cor...
متن کامل[IgA nephropathy].
IgA nephropathy is glomerular disease first described in 1968 by Berger, named after him Morbus Berger. The disease is characterized by the presence of IgA dominant or codominant immunoglobulin deposits in glomerular mesangium which can be demonstrated by immunofluorescence. Clinical manifestations of IgA nephropathy in the majority of cases is hematuria which can be macro or microscopic, isola...
متن کاملIgA Nephropathy.
IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international collaborative efforts have led to important discoveries that have improved our understanding of some of the key steps involved in the immunopathogenesis of IgAN. Furthermore, establishment of multicenter networks has contributed to rigorous design and execution of clinical trials that have provided importan...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2011
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfr664